Erratum: Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer
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Pulmonary Artery Sarcoma Overexpressing Platelet-derived Growth Factor Receptor α
Pulmonary artery sarcoma is highly malignant and easily metastasizes to the systemic organs. Both the introduction of novel diagnostic procedures and the development of new treatment modalities are required to achieve long-term survival. Several studies have shown that platelet-derived growth factor receptor α (PDGFRα) gene amplification is frequently observed in pulmonary artery sarcoma. PDGFR...
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Human cytomegalovirus (HCMV) is a widely distributed herpesvirus that causes significant morbidity in immunocompromised hosts. Inhibitors of viral DNA replication are available, but adverse effects limit their use. Alternative antiviral strategies may include inhibition of entry. We show that soluble derivatives of the platelet-derived growth factor receptor alpha (PDGFR-alpha), a putative rece...
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متن کاملThe platelet-derived growth factor alpha-receptor is encoded by a growth-arrest-specific (gas) gene.
Using the Escherichia coli lacZ gene to identify chromosomal loci that are transcriptionally active during growth arrest of NIH 3T3 fibroblasts, we found that an mRNA expressed preferentially in serum-deprived cells specifies the previously characterized alpha-receptor (alphaR) for platelet-derived growth factor (PDGF), which mediates mitogenic responsiveness to all PDGF isoforms. Both PDGFalph...
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ژورنال
عنوان ژورنال: Nature Microbiology
سال: 2016
ISSN: 2058-5276
DOI: 10.1038/nmicrobiol.2016.111